Custom PNA Synthesis: Unrestricted "Full-Spectrum" Customization
Stop compromising your biology due to synthesis limitations. While others reject complex designs, we deliver the exact molecule your research requires.
Built on 20 Years of PNA Innovation
We are the pioneers of Dynamic Chemical Labelling (DCL), powered by our own custom-engineered PNA modifications. From PNA-encoded chemical libraries to breakthrough chemistries that enable orthogonal protecting groups, Destina delivers the high-performance tools your research demands.
The Value of Experience
We drastically reduce your "trial and error" cycle. By ensuring an optimal design from the start, we shorten development timelines for novel therapeutic tools and increase success rates in downstream validation.
Don't Redesign Your Experiment
Stop choosing sub-optimal target regions just because standard manufacturers can't handle complex chemistry.
Standard Manufacturers
- ✕ Reject sequences with >5 consecutive Guanines.
- ✕ Limited modification menu.
- ✕ "Trial & Error" approach to design.
Destina Genomics
- ✓ Unrestricted Design: Complex hairpins & G-rich probes.
- ✓ Advanced Mods: Gamma-modified and tail modifications.
- ✓ Expert Support: 20+ years ensuring correct design first time.
Global Partnerships & Scientific Validation
Engineered for Performance
Beyond standard synthesis, our PNA technology offers superior biological stability and precision.
Total Biostability
Neutral polyamide backbone completely resistant to nucleases and proteases. Ideal for in vivo, serum, and long-term storage without signal fading.
Single-Base Precision
Significantly more sensitive to mismatches than DNA probes. A single mutation destabilizes the complex entirely, enabling 100% accurate SNP detection.
Backbone Engineering
Fine-tune hybridization strength and solubility with gamma-PNAs and tail modifications for "undruggable" targets and ASO applications.
Our Service Workflow
A streamlined process from complex design to delivery.
Submit Sequence
Upload your sequence file or paste your design via our contact form.
Expert Review
Our chemists review for feasibility, solubility, and modification needs.
Synthesis & QC
Synthesis followed by HPLC purification and Mass Spec verification.
Express Delivery
Receive your PNAs with full QC reports. No EU customs delays.
Reliable EU Manufacturing
Based in Granada, Spain
We are one of the few specialized PNA producers in Europe. This provides a reliable supply chain with no import delays for EU partners.
Ready to Transform Your Liver Safety Assessment?
Purchase your kit directly or contact our specialists for support.