LiverAce™ SinglePlex Kit

The gold-standard for PCR-Free detection of the early-detection biomarker miRNA-122. This assay offers unmatched specificity for rapid screening and precise quantification of liver injury.

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Key Features

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Unmatched Specificity: Accurately analyze circulating miR-122 to confirm the liver as the source of injury.
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PCR-Free Workflow: No RNA extraction, cDNA synthesis, or amplification steps required.

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Complete "All-in-One" Kit: Includes a 96-well plate and all necessary reagents, including standards for quantification.
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Broad Compatibility: Validated on Luminex xMAP®, Merck SMCxPRO®, and Quanterix SR-X® platforms. For more information on ELISA and chemiluminescence-based detection platforms, please contact us.

Product Characteristics

Kit Specifications

Parameter	Value
Analytes	miRNA-122
Platform	Luminex xMAP® (Validated on MAGPIX®, etc.)
Detection Method	PCR-Free Dynamic Chemical Labelling (DCL)
Time to Result	< 5 Hours
Sample Volume	25 µL
Sample Type	Serum, Plasma
Quantification Range	Absolute (Calibrators included)

Performance Characteristics

Assay Sensitivity

Analyte	LOD (pg/mL)	LLOQ (pg/mL)
miR-122	2.4	21

Precision

Analyte	Intra-assay %CV	Inter-assay %CV
miR-122	< 10%	< 20%

Assay Procedure

Simple, Streamlined, Superior

1. Add Sample

2. Hybridize

3. Label

4. Read

Applications & Research Fields

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Pharma R&D & Drug Development
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CROs & Service Labs
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Preclinical Safety Assessment
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Liver Toxicity (DILI) Screening

Documentation

To ensure you receive the latest version of our documentation, these files are available upon request.

Scientific Proof

Review the clinical evidence supporting our biomarkers and the DCL technology powering the LiverAce™ assays.

Key Publications (Biomarkers)

Clinical evidence supporting miR-122 as a superior biomarker for drug-induced liver injury.

Key Publications (LiverAce™ on Luminex platforms)

Foundational papers on the Dynamic Chemical Labelling (DCL) technology that powers LiverAce™ assays on Luminex platforms.

Ready to Transform Your Liver Safety Assessment?

Contact our specialists to discuss your research needs, request a quote, or inquire about our free evaluation kits.

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