LiverAce™ SinglePlex Kit
The gold-standard for PCR-Free detection of the early-detection biomarker miRNA-122. This assay offers unmatched specificity for rapid screening and precise quantification of liver injury.
Key Features
- Unmatched Specificity: Accurately analyze circulating miR-122 to confirm the liver as the source of injury.
- PCR-Free Workflow: No RNA extraction, cDNA synthesis, or amplification steps required.
- Complete "All-in-One" Kit: Includes a 96-well plate and all necessary reagents, including standards for quantification.
- Broad Compatibility: Validated on Luminex xMAP®, Merck SMCxPRO®, and Quanterix SR-X® platforms. For more information on ELISA and chemiluminescence-based detection platforms, please contact us.
Product Characteristics
Kit Specifications
| Parameter | Value |
|---|---|
| Analytes | miRNA-122 |
| Platform | Luminex xMAP® (Validated on MAGPIX®, etc.) |
| Detection Method | PCR-Free Dynamic Chemical Labelling (DCL) |
| Time to Result | < 5 Hours |
| Sample Volume | 25 µL |
| Sample Type | Serum, Plasma |
| Quantification Range | Absolute (Calibrators included) |
Performance Characteristics
Assay Sensitivity
| Analyte | LOD (pg/mL) | LLOQ (pg/mL) |
|---|---|---|
| miR-122 | 2.4 | 21 |
Precision
| Analyte | Intra-assay %CV | Inter-assay %CV |
|---|---|---|
| miR-122 | < 10% | < 20% |
Assay Procedure
Simple, Streamlined, Superior
1. Add Sample
2. Hybridize
3. Label
4. Read
Applications & Research Fields
- Pharma R&D & Drug Development
- CROs & Service Labs
- Preclinical Safety Assessment
- Liver Toxicity (DILI) Screening
Documentation
Scientific Proof
Review the clinical evidence supporting our biomarkers and the DCL technology powering the LiverAce™ assays.
Key Publications (Biomarkers)
Clinical evidence supporting miR-122 as a superior biomarker for drug-induced liver injury.
Key Publications (LiverAce™ on Luminex platforms)
Foundational papers on the Dynamic Chemical Labelling (DCL) technology that powers LiverAce™ assays on Luminex platforms.
Ready to Transform Your Liver Safety Assessment?
Contact our specialists to discuss your research needs, request a quote, or inquire about our free evaluation kits.